Dapoxetine+sildenafil is used in the treatment of premature ejaculation and erectile dysfunction in adult men. Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation than the man or his partner would like. This could lead to problems in a sexual relationship. Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity.
Dapoxetine+sildenafil contains Dapoxetine and Sildenafil. Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) that increases the serotonin levels in the brain, thereby increasing the time to ejaculate and improving the control over ejaculation. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor and works by relaxing the blood vessels. It can improve blood flow to the penis and helps to get an erection when sexually stimulated.
You should use this medicine exactly as prescribed by the doctor. The common side-effects of Dapoxetine+sildenafil are dizziness, headache, nausea (feeling sick), stuffy nose, facial flushing (reddening of the face), indigestion, dry mouth, and vision problems such as light sensitivity or blurred vision. These side effects usually resolve without requiring medical attention. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Dapoxetine+sildenafil if you are allergic to any contents of it. Do not take Dapoxetine+sildenafil if you have severe heart or liver problems, a recent history of heart attack or stroke, hypotension (low blood pressure), eye diseases or vision problems, a history of fainting, and mania or depression. Inform your doctor if you are taking medicines such as nitrates (to treat blood pressure or chest pain), antidepressants, antibiotics, or painkillers. Dapoxetine+sildenafil should not be taken by children and women. It should be used with caution in the elderly. Do not take excessive amounts of alcohol while using Dapoxetine+sildenafil as it may impair the ability of erection and increase the risk of side effects. Dapoxetine+sildenafil may cause dizziness and affect vision, so do not drive or operate heavy machinery if you are not fully alert.
Read moreIf you have any questions about the drugs you are taking, or the drugs you are taking, consult your doctor immediately. Dapoxetine+sildenafil should not be taken by anyone under 18 years of age.
Case 1. Combine two tablets of Dapoxetine with one tablet of sildenafil.If you are taking the combination tablet, take it as advised by your doctor.
If you forget to take a tablet, take it as soon as you remember. But, if it is almost time for your next dose, skip the missed dose and take the next tablet at the same time.
Avoid large and heavy meals that contain alcohol while taking Dapoxetine+sildenafil as it may cause drowsiness. Take the medicine with a heavy meal such as steak, meatloaf, or seafood, since it can affect your ability to get an erection.
Do not take it more than once a day.
your doctor may adjust your dosage based on your response and any side effects.
1. If you are not sure about the dosage, talk to your doctor.
2. Take the medicine at the same time every day as prescribed by your doctor.
3. In the event that you have taken a drug that makes you drowsy, do so with a cool hand. Do not drive or do anything that could be dangerous while you are taking this medicine.
4. Avoid alcoholic beverages and excessive alcohol while using Dapoxetine+sildenafil.
5. Do not take more medicine than your doctor prescribes.
6. Avoid consuming grapefruit or grapefruit juice while taking Dapoxetine+sildenafil as it may cause dizziness and affect your ability to get an erection.
7. Do not take the combination tablet if you are not sure about your medicine.
8. Inform your doctor if you have any side effects such as difficulty in breathing, facial flushing, swelling of your feet or lower legs, headache, dizziness, or fainting.
9.
Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.
You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.
There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-
• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).
• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets
for chest pain or use Rectogesic ointment?
• Nicorandil (Ikorel), used to treat angina
• Cimetidine, used to treat stomach or duodenal (peptic) ulcers
• Theophylline, used to treat asthma
• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin
• Anti-fungals such as itraconazole and ketoconazole
• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone
• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide
• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat
• Recreational drugs:- amyl nitrate (poppers)
If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.
Read available consultation questionnaire information online for “Tadalafil can’t be taken”Tadalafil is the generic version of the drugsCialis, Levitra,inersurancecardwhich are supported by patents covering improvements in sexual function and lower urinary tract symptoms (Lupus)
Tadalafil is available in the following medications by manufacturer:
•
The most common combinations are :-
• Tadalafil for daily use. Thisichever is the highest dose, then continue with the evening dose.
• Tadalafil for once daily use. This combination needs to be taken at the same time each day to reach the results it will give.
This combination needs to be taken at the evening dose.
This combination needs to be taken every day to reach the same result.
There are several dosage forms of Tadalafil, so you can take it at a time.
Please note:
The dosage of Tadalafil will depend on the treating medicinal product, patient and other factors you may have in mind.
As the pharmaceutical industry expands, its costs will skyrocket. One major reason is the prevalence of erectile dysfunction (ED) in men. The prevalence of ED in men affects a significant percentage of the population. According to statistics, roughly 10% of men in the United States experience ED. This percentage is particularly high for men with prostate cancer, who are more likely to experience ED, compared to men with other types of cancer. One of the primary reasons men with ED are at increased risk of developing cancer is because of the high-risk factors that can increase their risk of developing ED.
The National Institute on Aging (NIA) is investigating the role of phosphodiesterase type 5 (PDE5) inhibitors like Cialis (tadalafil), Viagra (sildenafil), and Levitra (vardenafil) in the treatment of ED. In this article, we will explore these PDE5 inhibitors and discuss their possible role in ED management.
The National Institutes of Health (NIDA) has conducted a large-scale study to investigate the role of phosphodiesterase type 5 (PDE5) inhibitors like Cialis (tadalafil), Viagra (sildenafil), and Levitra (vardenafil) in the treatment of ED. It found that patients with ED who had a history of PDE5 inhibitors, or those taking these drugs for an extended period of time, were more likely to experience ED than those on the placebo.
The National Institutes of Health found that phosphodiesterase type 5 inhibitors are not generally more effective than the other PDE5 inhibitors, and they are generally more effective than the placebo. They do not increase the risk of ED, and they do not increase the likelihood of ED.
PDE5 inhibitors like Cialis (tadalafil), Viagra (sildenafil), and Levitra (vardenafil) are currently on the market. They are categorized as PDE5 inhibitors based on their structure and chemical structure. There are three different PDE5 inhibitors: PDE5, Phosphodiesterase Type 5 (PDE5), and Phosphodiesterase Type 5 inhibitors (PDE5). PDE5 inhibitors are classified as PDE5 inhibitors in the following ways:
PDE5 inhibitors offer a number of benefits, including the reduction of the risk of ED. The most common benefits of PDE5 inhibitors include:
For those looking to improve their sexual performance, the benefits of PDE5 inhibitors are typically seen in a number of different ways. For example, some men might have reduced the incidence of ED as a result of their PDE5 inhibitors treatment. Others might find that their PDE5 inhibitors help them achieve an erection.
The most common side effects of PDE5 inhibitors include:
It is also important to note that the PDE5 inhibitors that are currently used in men with ED should not be taken if you are already taking nitrates. This is because this drug is used to treat pulmonary hypertension. PDE5 inhibitors do not increase blood pressure, but can help to reduce the risk of heart attacks, strokes, and heart failure.
There is no specific reason men should not take PDE5 inhibitors, but they should still be taken if they are already taking the medication. When used to treat pulmonary hypertension, these medications can be very effective in treating ED.
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1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
----------ilippines Tripathi D. Tripathi, B. P. Catania, S. S. Kothari, M. A. Kothari, and B.